| Summary |
In the pharmaceutical plants , some technics processes refer to storage and preparation . Such as , storage of purified water comes to storage tank , WFI comes to WFI storage tank etc.
Learning about this system , Watertown supplies design ,manufacture , instillation , measure and validation supporting sevice for customers .
To reach special requirements of biological engineering equipment , technics vessel must have good structure complying with requirements of pharmaceutical and sanitation .
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| Vessel characteristics |
Machining as the pressure vessel quality assurance system .
- Chemical stability of material ---undissolved , innoxious , stainless steel 304, 316L.
- Surface treatment ---- mechanical and electro-polishing for the contact surface with media .
- Connection mode ---- argon protection welding.
- Structure ---- aseptic and sanitation.
- Seal ---- a good seal system , should regarde to the seal level , working pressure , working temperature , anti-cavitation , sterilization ,clean , passivation .
- Slope : solution drain by itself gravity .
- Diameter and length ratio of nozzle and dead leg of pipeline ----if the length and diameter ratio is big , matters tend to remain , microorganisms are prone to grow up .
- Easy connection --- CIP and SIP connection easily .
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| Advantages |
The requirements for the material and surface treatment are same as vessel basically, connection with argon protection welding and sanitation clamp joint . Inner circular arc angles of tube and fittings both comply with the requirements of biological engineering equipment .According to the different requirements of technics , attachments may include:
- Chemical stability of material ---undissolved , innoxious , stainless steel 304, 316L.
- Spray device ---- coverage rate is 100%, to assure physical appearance and chemical property of media are same in different places.
- Meters detection ----- level meter , temperature meter , PH , conductivity meter are using for the supervision physics and chemical state of medias in vessel .
- Manhole ---a passage for clean and repair persons .
- Sight glass---- to assure operator check the inner state of equipments .
- Weightometer--- to weigh for liquid medicine .
- Jacket ---- to regulate the inner temperature of vesel , satisfy technics requires for the temperature state .
- Insulation ---- according to the requirements of technics or comparing with ambient , reduce energy consumption , prevent operator from injuring , should have the insulation measure . The insulation material not contain asbestos and chloride .
- Air filter or clean nitrogen supply system --- to prevent uncondensable air coming into vessel , presure inside and outside of vessel are same .
- Pump & valves ---type is very crucial when using largely .
- Consideration for requirements of CIP and SIP . For example , 1. for the mixing tank of liquid medicine , using pneumatic diaphragm tank bottom valve . 2. WFI using KLH sanitation pump .
- Churn-dasher ---- stir for liquid medicine adequately .
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