| Summary |
Purified water preparation system can effect pharmaceutical water directly, it submits to GMP critical system .
RO and EDI equipment are designed for application in a wide range of purified water preparation of pharmaceutical plant and core equipment .
Reverse osmosis is also called opposite osmosis relative to “osmosis”.
Osmosis is a process of water from the dilute solution flows to concentrate through the semipermeable membrane automatically .
For the reverse osmosis , in the action of applied pressure ,water from the concentrate flows to the dilute solution , it is un-optionala .
EDI is also called continuous electro deionization , it brings electrodialysis and ion exchange technology together as one, By the action of electric field , ion directional movement then removes the salts . The working of EDI also a process of resin rebirth continuously ,EDI device is after RO system .
Using RO + EDI , water quality can reach16MΩ•CM, no any acid and alkali , work automatically for full process . |
| Characteristic of purified water produced by RO and EDI |
- Water quality is good , conductivity can reach 16MΩ•CM;
- Degree of stability for water quality is optimal ;
- Can produce ultra-purified water complying with use`s requirement continuously ;
- Modularization , full automatic control .
- No need rebirth of acid and alkali , no sewage drain ;
- Operate simply , low labor strength ;
- Can not stop machine for rebirth;
- No rebrith equipment and chemical storage and transportation ;
- Structure of equipment is compact , lillte location .
- Running and maintenance cost is low .
- Control system : to meet the user different control requirements , using PLC automatic control technology .
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| Advantage and characteristic of purified water preparation system produced by Watertown |
Watertown works is engaged in design , manufacture , instillation , commissioning , validation service of purified water preparation system , including RO and EDI . The full set of purified water preparation system has following characteristic :
- Keeping a good relationship with suppliers:
Watertown experienced in purified water equipment for several years , keeping a good relationship with suppliers , guaranteed in supply of components , quality and work date .
- Professional engineering design team :
Watertown possess of engineering experts at working on pharmaceutical plant design , chemical engineering , automatic control , welding , GMP validation etc. Basing on the knowledge and water quality , they offer GMP requirements , fitting for purified water preparation technical protocol .
- Advantage of manufacture:
Watertown experienced in purified water equipment for several years , such as : argon protection automatic orbit welding , electro chemical polish, FAT plant , can assure quality stable and credible .
Modularization design is the guiding ideology for whole system , assemble RO , EDI pre-treatment equipment , post treatment etc acoording to equipment capacity and configuration . The method reduces time of working , improves instillation and commissioning frequency at site .
Selecting for GMP requirements and customer cost budgeting basing on client requirements , such as pre-treatment , RO , EDI , material of post treatment .
- Linkage with storage tank and mode of recycle production
For RO+EDI , controlled by the level of purified water storage tank , in order to reduce biological deposit on the membrane , system always in the mode of production and recycle .
- Softening agent for pre-treatment
Not add ant chemical in the process of production , not use scale-inhibitor .
- Two sets of pre-treatment
On the basis of customer requirements , to guarantee RO and EDI production continuously , equip with two sets of pre-treatment.
To keep stable and credible quality , using hydranautics or DOW components .
It is better to use hot sterilization type RO components suggested by Watertown, the RO components can bear pasteurization , not use chemical in the production , cleaning and sterilization
EDI module made by America IONPURE or Electropure.
Hot water sterilization module is preferred , can sterilized by hot water . Combination with hot sterilization RO components as a whole purified water preparation system no need chemical completely .
Pump and valves are frequent mobile components , so need match with products . The common brands : Grundfos , Burket , GEMU, Alfa Laval etc.
- Crucial instruments and automatic control
According to different technical protocol , select different instrument and control configurations.
PLC and HMI are the common control mode , equipping with conductivity meter , temperature meter , flow meter , pressure meter etc. the function as following :
To set and display techincs parameter .
Pre-treatment system work , backwash operation and control .
operation and control of RO unit
Operation and control of EDI
Operation and control of high temperature sterilization system.
Linkage with storage tank sensor.
Display and treatment of alarm : level high and low alarm of feed water and soft water tank , flow high and low alarm of permeated water and concentrate EDI , conductivity high alarm of permeated water RO , conductivity high alarm of water output EDI .
Making use of argon protection automatic orbit welding , the welding process is the implementation of mature welding process . Welding technics evaluation prior to welding , record the parameter during the welding process .
- Polishing and passivation
For the products , treated by mechanical polishing , electro-polishing , passivation and measure & record for roughness after treatment according to the requirements of ASME BPE and ISPE guidance in the GMP .
Same as other products produced by Watertown , provide the trial and validation service for system on the basis of guide of ISPE, including DQ, IQ , PQ,FAT, SAT etc . |
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