| Summary |
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| ??WFI preparation system is the key system for GMP. Multi-effect distillation unit is crucial equipment for WFI preparation system. The multi-effect distillation unit produced by Watertown using high temperature and pressure operation , to assure pyrogen-free WFI producing stable . Distilled water produced by Multi-effect distillation unit complys with requirements of U.S. , Europ ,Japan and China pharmacopoeia for WFI . Multi-effect distillation unit is the strongest product of Watertown , our goal is to design and manufacture the best distillation unit in China . |
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Technical characteristic |
- Material : puressure vessel body and pipeline connecting with distilled water , rebirth pure steam are 316L , sealed material is PTFE, other materials including frame are 304 .
- Three stage separator : feed water in equipment can separate by film evaporation , gravity and special seporator .
- Electro-polish : to assure WFI quality and increase the life of equipment , stainless steel surface treated by electro-polish .
- Double tube sheets : The design for external pre-heater ,condenser and I effect evaporator are double tube sheets , comply with requirements of cGMP, can prevent the possibility of low sanitation level media polluting system .
- Heat-exhange tube using seamless : the intensity and wearing property of seamless tube is better , can keep a good state in the process of machine , welding , expansion joint and contraction , to avoid any plant steam , feed water and cooling water leakage into clean distilled water and rebirth steam .
- Three dimensional bend : To avoid welding , using stainless steel tube in the pipeline .
- Automatic welding: To assure welding quality , make use of automatic argon protection orbit welding in the connection of pipeline and parts .
- Heat insulation : For evaporator and pre-heater , using un-chlorine , un-asbestus mineral heat insulation , external covered by stainless steel .
- Feed water pre-treatment : No expensive purified water equipment , deionized water or RO water which conductivity are less than 5μS/cm can as feed water .
- Economic and energy-saving :Rebirth steam in each effect utilizes step by step , so the operating factor of plant steam is very high , has a obvious energy-saving effect . Along with the effects of evaporator increase , the effect are more obvious . At the same time , quantity of cooling water can decrease considerably .
- Control system : to reach the different customer`s requirements , using PLC control technology . From the determine and distribution of pure steam quality to higher control , such as each media continuous regulation , storage system linkage , classification password control and evaporation quantity etc, we can check carefully .
- Non-paper recorder : to record the actual producing situation using non-paper recorder.
- Whole machine performance plant test : in the plant of whole machine test , according to decided procedure , test for the whole machine .
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Working principle of MS-T series distillation unit |
| ??Working flow chart of MS-T series distillation unit as following : Feed water is heating by plant steam in I effect evaporator , then enter into posterior each effect pre-heater , pre-heated by plant steam ; rebirth steam and distilled water are heating for them in the condensers ;In the top of evaporator , after water separator , enters evaporation tube uniformly distributed , becomes film type stream in the evaporation tube ; Because very thin, so after evaporation , can become rebirth steam very quickly , the feed water which are un-evaporated transport to the next effect , as the feed water , this process repeats on and on until the feed water in last effect are un-evaporated , drain as condensate ; The rebirth steam (evaporated feed water ), ascends in the evaporator spirally , enters pure steam pipeline as next effect pyrogen gets through middle and top special seperator ; In the evaporator , pyrogen of rebirth steam absorbed by feed water condenses distilled water ; the processes for each effect are same , distilled water of each effect and rebirth steam of last effect are collected by condenser , heating change with cooling water and feed water , after cooling , become distilled water ; On-line detection for conductivity , qualified distilled water as WFI output , unqualified drain |
| ??After three times separation , feed water turns into rebirth steam which are clean .The first time evaporation , feed water enters evaporator , then flow , at the same time evaporates ;The evaporated feed water in the lower extreme of evaporator back turns , in the action of gravity , foreign matters separate in the under-part , this is the second separation time ; For the third time , the rebirth steam (evaporated feed water ) ascends in the evaporator spirally , separates in the middle and top special separator . The cooling water only gets through condenser , can drop temperature for distilled water produced by each effect and rebirth steam .Plant steam is heating for feed water in I effect evaporator and pre-heater , becomes condensate after absorbing pyrogen , then drain out of machine . A portion of air in feed water can not condense , called uncondensable air , according to the automatica control degree , they can exhaust by device in the top of evaporator. |
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- plant steam
- condensate drain
- concentrate drain
- cooling water out
- distilled water
- cooling water in
- feed water in
- uncondensable air exhaust
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Working principle of MS-T series multi-effect water still |
| ??Working flow chart of MS-T series distillation unit as following : Feed water is heating by plant steam in I effect pre-heater , then enters into posterior each effect pre-heater , pre-heated by plant steam condensate ; rebirth steam and distilled water are heating for them in the condensers ;In the top of evaporator , after water separator , enters evaporation tube uniformly distributed , becomes film type stream in the evaporation tube ; Because very thin, so after evaporation , can become rebirth steam very quickly , the feed water which are un-evaporated transport to the next effect , as the feed water , this process repeats on and on until the feed water in last effect are un-evaporated , drain as condensate ; The rebirth steam (evaporated feed water ), ascends in the evaporator spirally , enters pure steam pipeline as next effect pyrogen gets through middle and top special seperator ; In the evaporator , pyrogen of rebirth steam absorbed by feed water condenses distilled water ; the processes for each effect are same , distilled water of each effect and rebirth steam of last effect are collected by condenser , heating change with cooling water and feed water , after cooling , become distilled water ; On-line detection for conductivity , qualified distilled water as WFI output , unqualified drain . |
| ??After three times separation , feed water turns into rebirth steam which are clean .The first time evaporation , feed water enters evaporator , then flow , at the same time evaporates ;The evaporated feed water in the lower extreme of evaporator back turns , in the action of gravity , foreign matters separate in the under-part , this is the second separation time ; For the third time , the rebirth steam (evaporated feed water ) ascends in the evaporator spirally , separates in the middle and top special separator . |
| ??The cooling water only gets through condenser , can drop temperature for distilled water produced by each effect and rebirth steam .Plant steam is heating for feed water in I effect evaporator and pre-heater , becomes condensate after absorbing pyrogen , then drain out of machine . A portion of air in feed water can not condense , called uncondensable air , according to the machine type , they can exhaust by device in the top of evaporator. |
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- plant steam
- condensate drain
- concentrate drain
- cooling water out
- distilled water
- cooling water in
- feed water in
- uncondensable air exhaust
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Difference between S series and T series |
| ??Seporator mode : seporation mode of S series is very simple , but the mode for T series manufactured by Watertown . |
| ??Product specification model range : when large , S type is better , see product type list . |
| ??Pyrogen for pre-heater : the pyrogen for S series is water , but for T type is steam . |
Type selection table for MS-T series multi-effect water stills |
| Model |
Capacity ( kg/h ) |
Working pressure
( 0.3MPa ) |
Workig pressure
( 0.6MPa ) |
| 3 |
4 |
5 |
6 |
3 |
4 |
5 |
6 |
| MS100 T |
100 |
100 |
- |
- |
150 |
150 |
- |
- |
| MS300 T |
300 |
300 |
- |
- |
350 |
350 |
- |
- |
| MS500 T |
- |
500 |
500 |
- |
- |
750 |
750 |
- |
| MS750 T |
- |
750 |
750 |
- |
- |
1125 |
1125 |
- |
| MS1000 T |
- |
- |
1000 |
1000 |
- |
- |
1500 |
1500 |
| MS1500 T |
- |
- |
1500 |
1500 |
- |
- |
2250 |
2250 |
| MS2000 T |
- |
- |
2000 |
2000 |
- |
- |
3000 |
3000 |
| MS3000 T |
- |
- |
3000 |
3000 |
- |
- |
4500 |
4500 |
| MS4000 T |
- |
- |
- |
4000 |
- |
- |
- |
6000 |
| MS5000 T |
- |
- |
- |
5000 |
- |
- |
- |
7500 |
| MS6000 T |
- |
- |
- |
6000 |
- |
- |
- |
9000 |
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Type selection table for MS-S series multi-effect water stills |
| Model |
Capacity ( kg/h ) |
| Working pressure ( 0.3MPa ) |
| 3 |
4 |
5 |
6 |
| MS100 S |
100 |
100 |
- |
- |
| MS300 S |
300 |
300 |
- |
- |
| MS500 S |
- |
500 |
500 |
- |
| MS750 S |
- |
750 |
750 |
- |
| MS1000 S |
- |
- |
1000 |
- |
| MS1500 S |
- |
- |
1500 |
1500 |
| MS2000 S |
- |
- |
2000 |
2000 |
| MS3000 S |
- |
- |
3000 |
3000 |
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